YES1 抗体 (AA 441-541)
Quick Overview for YES1 抗体 (AA 441-541) (ABIN754798)
抗原
See all YES1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 441-541
-
交叉反应
- 人, 小鼠
-
预测反应
- Rat,Dog,Cow,Pig,Chicken,Rabbit,Guinea Pig
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human YES1
-
亚型
- IgG
-
-
anti-V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1 (YES1) (pTyr426) antibody
YES1 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1 (YES1) (AA 1-155) antibodyYES1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1 (YES1) (AA 1-80) antibodyYES1 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 3C6 unconjugated
anti-V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1 (YES1) (AA 1-543) antibodyYES1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2D5 unconjugated
anti-V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1 (YES1) (AA 284-541) antibodyYES1 适用: 人, 小鼠 WB, IHC, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1 (YES1) (AA 1-543) antibodyYES1 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 2F4 unconjugated
anti-V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1 (YES1) (Center) antibodyYES1 适用: 人, 小鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1 (YES1) antibodyYES1 适用: 人, 犬, 斑马鱼 WB, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1 (YES1) (AA 1-250) antibodyYES1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1 (YES1) (AA 10-193) antibodyYES1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2F3E6 unconjugated
-
-
应用备注
-
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
-
有效期
- 12 months
-
-
- YES1 (V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1 (YES1))
-
别名
- YES1
-
背景
-
Synonyms: Yes, c-yes, HsT441, P61-YES, Tyrosine-protein kinase Yes, Proto-oncogene c-Yes, YES1
Background: Non-receptor protein tyrosine kinase that is involved in the regulation of cell growth and survival, apoptosis, cell-cell adhesion, cytoskeleton remodeling, and differentiation. Stimulation by receptor tyrosine kinases (RTKs) including EGRF, PDGFR, CSF1R and FGFR leads to recruitment of YES1 to the phosphorylated receptor, and activation and phosphorylation of downstream substrates. Upon EGFR activation, promotes the phosphorylation of PARD3 to favor epithelial tight junction assembly. Participates in the phosphorylation of specific junctional components such as CTNND1 by stimulating the FYN and FER tyrosine kinases at cell-cell contacts. Upon T-cell stimulation by CXCL12, phosphorylates collapsin response mediator protein 2/DPYSL2 and induces T-cell migration. Participates in CD95L/FASLG signaling pathway and mediates AKT-mediated cell migration. Plays a role in cell cycle progression by phosphorylating the cyclin-dependent kinase 4/CDK4 thus regulating the G1 phase. Also involved in G2/M progression and cytokinesis.
-
基因ID
- 7525
-
UniProt
- P07947
-
途径
- CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling
抗原
-
