SNAP25 抗体 (C-Term)
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Quick Overview for SNAP25 抗体 (C-Term) (ABIN8044515)
抗原
See all SNAP25 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- C-Term
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原理
- Anti-SNAP25 Antibody
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- identical to the related rat,mouse sequences.
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产品特性
- Anti-SNAP25 Antibody. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human SNAP25, identical to the related rat and mouse sequences.
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亚型
- IgG
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anti-Synaptosomal-Associated Protein, 25kDa (SNAP25) (AA 1-206) antibody
SNAP25 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Synaptosomal-Associated Protein, 25kDa (SNAP25) (AA 1-206) antibodySNAP25 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Synaptosomal-Associated Protein, 25kDa (SNAP25) (C-Term) antibodyVerified SNAP25 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Synaptosomal-Associated Protein, 25kDa (SNAP25) antibodySNAP25 适用: 人 WB, IHC, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal 1E6 unconjugated
anti-Synaptosomal-Associated Protein, 25kDa (SNAP25) (AA 166-206) antibodySNAP25 适用: 大鼠, 小鼠 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Synaptosomal-Associated Protein, 25kDa (SNAP25) antibodySNAP25 适用: 人 WB, IHC, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal 1G2 unconjugated
anti-Synaptosomal-Associated Protein, 25kDa (SNAP25) (AA 192-206) antibodySNAP25 适用: 人, 大鼠, 小鼠, 小鸡, 斑马鱼, Hamster, Goldfish WB, IHC, ELISA, IP, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Synaptosomal-Associated Protein, 25kDa (SNAP25) (AA 31-130) antibodySNAP25 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4A3 unconjugated
anti-Synaptosomal-Associated Protein, 25kDa (SNAP25) (C-Term) antibodySNAP25 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Synaptosomal-Associated Protein, 25kDa (SNAP25) antibodySNAP25 适用: 人, 大鼠, 小鼠, Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Rat, Human, MouseWestern blot, 0.1-0.5 μg/mL, Rat, Human, Mouse
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Sodium azide, Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- SNAP25 (Synaptosomal-Associated Protein, 25kDa (SNAP25))
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别名
- SNAP25
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背景
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Background: Synaptosome-associated protein of 25,000 daltons also known as SNAP-25 is a protein which in humans encodes a 25-kD protein of 206 amino acids. It was first investigated as a neuron-specific gene preferentially expressed in mouse hippocampus. The tSNARE (the target-membrane soluble NSF-attachment protein receptor, where NSF is N-ethylmaleimide-sensitive fusion protein) synaptosomal-associated protein of 25 kDa (SNAP-25) is expressed in pancreatic B-cells and its cleavage by botulinum neurotoxin E (BoNT/E) abolishes stimulated secretion of insulin. In the nervous system, two SNAP-25 isoforms (a and b) have been described, which are produced by alternative splicing. Nagy et al. (2004) identified mammalian Snap25a and Snap25b as targets of protein kinase A, a key regulator of neurosecretion that primes slowly releasable pools and readily releasable pools of secretory vesicles. SNAP-25 inhibits P/Q- and L-type voltage-gated calcium channels located presynaptically and interacts with the synaptotagmin C2B domain in Ca2+-independent fashion. In glutamatergic synapses SNAP-25 decreases the Ca2+ responsiveness, while it is naturally absent in GABAergic synapses.
Gene Full Name: synaptosome associated protein 25
Sequence Similarities: Belongs to the SNAP-25 family.
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分子量
- 40-50 kDa, 80-140 kDa
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UniProt
- P60880
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途径
- Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
抗原
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