SNAP25 抗体 (AA 31-203) (Fluoro594)
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Quick Overview for SNAP25 抗体 (AA 31-203) (Fluoro594) (ABIN8044498)
抗原
See all SNAP25 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 31-203
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原理
- Anti-SNAP25 Antibody Fluoro594 Conjugated
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交叉反应 (详细)
- No cross reactivity with other proteins.
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预测反应
- Human SNAP25 shares 100% amino acid (aa) sequence identity with both mouse,rat SNAP25.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SNAP25 recombinant protein (Position: R31-L203). Human SNAP25 shares 100% amino acid (aa) sequence identity with both mouse and rat SNAP25.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- SNAP25 (Synaptosomal-Associated Protein, 25kDa (SNAP25))
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别名
- SNAP25
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背景
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Background: Synaptosomal-Associated Protein, 25 kDa (SNAP-25) is a Target Soluble NSF (N-ethylmaleimide-sensitive factor) Attachment Protein Receptor (t-SNARE) protein encoded by the SNAP25 gene found on chromosome 20p12.2 in humans. Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene.
Gene Full Name: synaptosome associated protein 25
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基因ID
- 6616
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UniProt
- P60880
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途径
- Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
抗原
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