SNAP23 抗体 (N-Term) (PE)
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北京 101111
Quick Overview for SNAP23 抗体 (N-Term) (PE) (ABIN8044458)
抗原
See all SNAP23 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Anti-SNAP23 Antibody PE Conjugated
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human SNAP23, which shares 94.4% amino acid (aa) sequence identity with mouse and rat SNAP23.
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亚型
- IgG
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anti-Synaptosomal-Associated Protein, 23kDa (SNAP23) (AA 1-211) antibody
SNAP23 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Synaptosomal-Associated Protein, 23kDa (SNAP23) (AA 1-210) antibodySNAP23 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Synaptosomal-Associated Protein, 23kDa (SNAP23) (AA 1-211) antibodySNAP23 适用: 人 WB, ELISA, IP, IHC (p) 宿主: 小鼠 Monoclonal 2F5-3D4 unconjugated
anti-Synaptosomal-Associated Protein, 23kDa (SNAP23) (N-Term) antibodySNAP23 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Synaptosomal-Associated Protein, 23kDa (SNAP23) (AA 1-211) antibodySNAP23 适用: 人 WB, ELISA, IHC, FACS, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Synaptosomal-Associated Protein, 23kDa (SNAP23) (AA 1-132) antibodySNAP23 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Synaptosomal-Associated Protein, 23kDa (SNAP23) (C-Term) antibodySNAP23 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Synaptosomal-Associated Protein, 23kDa (SNAP23) (AA 1-211) antibodySNAP23 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Synaptosomal-Associated Protein, 23kDa (SNAP23) (C-Term) antibodySNAP23 适用: 人, 小鼠, 大鼠 WB, IHC, FACS, ICC, IF, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Synaptosomal-Associated Protein, 23kDa (SNAP23) (AA 90-196) antibodySNAP23 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- SNAP23 (Synaptosomal-Associated Protein, 23kDa (SNAP23))
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别名
- SNAP23
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背景
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Background: SNAP23(Synaptosomal-Associated Protein, 23-KD), also called SNAP23A, is a protein that in humans is encoded by the SNAP23 gene. The SNAP23 gene has 8 exons, with the initiation codon located in exon 2. The SNAP23 gene is mapped on 15q15.1-q15.2. The SNAP23 cDNA encodes a 211-amino acid polypeptide with a predicted mass of 23 kD. Its amino acid sequence is 59 % identical to that of SNAP25. Northern blot analysis revealed that SNAP23 is ubiquitously expressed. SNAP23 is able to bind to multiple syntaxins as well as to multiple vesicle-associated membrane proteins. After relocation, SNAP23 is required for exocytosis, implying a crucial role in promoting membrane fusion. TIVAMP-containing vesicles were concentrated in the apical domain of epithelial cells. STX3A and SNAP23 were codistributed at the apical plasma membrane, where they formed N-ethyl maleimide-dependent SNARE complexes with TIVAMP and cellubrevin. SNAP23 is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion.
Gene Full Name: synaptosome associated protein 23
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基因ID
- 8773
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UniProt
- O00161
抗原
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