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Synaptophysin 抗体 (N-Term) (Biotin)

This 小鼠 单克隆 antibody specifically detects Synaptophysin in WB, IHC 和 ELISA. It exhibits reactivity toward 大鼠 和 小鼠.
产品编号 ABIN8044373
发货至: 中国
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Quick Overview for Synaptophysin 抗体 (N-Term) (Biotin) (ABIN8044373)

抗原

See all Synaptophysin (SYP) 抗体
Synaptophysin (SYP)

适用

  • 171
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大鼠, 小鼠

宿主

  • 117
  • 79
  • 1
  • 1
小鼠

克隆类型

  • 129
  • 69
单克隆

标记

  • 114
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This Synaptophysin antibody is conjugated to Biotin

应用范围

  • 114
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  • 27
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  • 12
  • 6
  • 3
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  • 1
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA

克隆位点

3G12
  • 抗原表位

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    N-Term

    原理

    Anti-SYP/Synaptophysin Antibody (monoclonal, 3G12) Biotin Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    identical to the related mouse,rat sequences.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human Synaptophysin, identical to the related mouse and rat sequences.

    亚型

    IgG2b
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    Synaptophysin (SYP)

    别名

    SYP

    背景

    Background: SYP (Synaptophysin) is located on the short arm of X chromosome (Xp11.23-p11.22). The protein is a synaptic vesicle glycoprotein with four transmembrane domains weighing 38 kDa. It is present inneuroendocrine cells and in virtually all neurons in the brain and spinal cord that participate in synaptic transmission. It acts as a marker for neuroendocrine tumors, and its ubiquity at the synapse has led to the use of synaptophysin immunostaining for quantification of synapses. Also, the protein binds cholesterol and is thought to targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with X-linked mental retardation (XLMR).

    Gene Full Name: synaptophysin

    基因ID

    6855

    途径

    Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity
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