SOCS2 抗体 (AA 96-198) (Fluoro647)
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Quick Overview for SOCS2 抗体 (AA 96-198) (Fluoro647) (ABIN8043743)
抗原
See all SOCS2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 96-198
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原理
- Anti-SOCS2 Antibody Fluoro647 Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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预测反应
- Human SOCS2 shares 96.1%,95.1% amino acid (aa) sequence identity with mouse,rat SOCS2,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SOCS2 recombinant protein (Position: R96-V198). Human SOCS2 shares 96.1% and 95.1% amino acid (aa) sequence identity with mouse and rat SOCS2, respectively.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))
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别名
- SOCS2
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背景
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Background: Suppressor of cytokine signaling 2 is a protein that in humans is encoded by the SOCS2 gene. This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signalling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10 and interferon-gamma (IFN-gamma). The protein encoded by this gene is found to interact with the cytoplasmic domain of insulin-like growth factor 1 receptor (IGF1R), and thus is thought to be involved in the regulation of IGF1R mediated cell signaling. By cytogenetic and radiation hybrid mapping, Yandava et al. (1999) mapped the SOCS2 gene to chromosome 12q21.3-q23.
Gene Full Name: suppressor of cytokine signaling 2
Sequence Similarities: Contains 1 SH2 domain.
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基因ID
- 8835
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UniProt
- O14508
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途径
- JAK/STAT Signaling, Response to Growth Hormone Stimulus
抗原
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