HSC70 Interacting Protein HIP 抗体 (N-Term) (Cy3)
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Quick Overview for HSC70 Interacting Protein HIP 抗体 (N-Term) (Cy3) (ABIN8043680)
抗原
See all HSC70 Interacting Protein HIP (ST13) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Anti-HSC70 Interacting Protein HIP/ST13 Antibody Cy3 Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- different from the related rat,mouse sequences by two amino acids.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human ST13, different from the related rat and mouse sequences by two amino acids.
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亚型
- IgG
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anti-Suppression of Tumorigenicity 13 (ST13) antibody
ST13 适用: 人, 猴 WB, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 3B10 unconjugated
anti-Suppression of Tumorigenicity 13 (ST13) antibodyKD Validated ST13 适用: 人 WB, FACS, IF (p) 宿主: 小鼠 Monoclonal 25GB8070 unconjugated
anti-Suppression of Tumorigenicity 13 (ST13) (AA 1-369) antibodyST13 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Suppression of Tumorigenicity 13 (ST13) (AA 1-58) antibodyST13 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B2 unconjugated
anti-Suppression of Tumorigenicity 13 (ST13) (AA 50-80) antibodyST13 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB2078 unconjugated
anti-Suppression of Tumorigenicity 13 (ST13) (AA 1-369) antibodyST13 适用: 人 WB, ELISA, FACS, IF, ICC 宿主: 小鼠 Monoclonal AT5C6 unconjugated
anti-Suppression of Tumorigenicity 13 (ST13) (AA 2-369) antibodyST13 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Suppression of Tumorigenicity 13 (ST13) antibodyST13 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Suppression of Tumorigenicity 13 (ST13) (AA 166-369) antibodyST13 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Suppression of Tumorigenicity 13 (ST13) (AA 41-90) antibodyST13 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow Cytometry, 1-3 μg/1x106 cells
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- HSC70 Interacting Protein HIP (ST13) (Suppression of Tumorigenicity 13 (ST13))
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别名
- ST13
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背景
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Background: ST13 (Suppression of Tumorigenicity 13), also known as P48 or HIP, is a protein that in humans is encoded by the ST13 gene. ST13 is an abundant, highly conserved protein that binds the major cytosolic chaperones heat-shock protein 70-kD (HSP70) and HSP90 during an intermediate stage of steroid receptor assembly, but is absent from the mature receptor complex. Zhang et al. (1998) mapped the ST13 gene to chromosome 22q13 by fluorescence in situ hybridization. They noted that colorectal, breast, and ovarian carcinomas frequently show loss of heterozygosity at this site. Using a yeast 2-hybrid assay, Hohfeld et al. (1995) showed that rat Hip bound Hsc70 (HSPA8). One Hip oligomer bound the ATPase domains of at least 2 Hsc70 Molecules, and binding was dependent on activation of the Hsc70 ATPase by Hsp40 (DNAJB1). Hip stabilized the ADP-bound form of Hsc70, which had a high affinity for a test protein substrate. Hohfeld et al. (1995) concluded that HIP contributes to interactions of HSC70 with target proteins through its own chaperone activity.
Gene Full Name: ST13 Hsp70 interacting protein
Sequence Similarities: Belongs to the FAM10 family.
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基因ID
- 6767
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UniProt
- P50502
抗原
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