SOD2 抗体 (C-Term) (HRP)
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北京 101111
Quick Overview for SOD2 抗体 (C-Term) (HRP) (ABIN8043586)
抗原
See all SOD2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-SOD2 Antibody HRP Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- different from the related mouse sequence by one amino acid,and from the related rat sequence by four amino acids.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human SOD2, different from the related mouse sequence by one amino acid, and from the related rat sequence by four amino acids.
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亚型
- IgG
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anti-Superoxide Dismutase 2, Mitochondrial (SOD2) (AA 25-222) antibody
SOD2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Superoxide Dismutase 2, Mitochondrial (SOD2) (AA 1-222) antibodySOD2 适用: 人 IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 8H3D2 unconjugated
anti-Superoxide Dismutase 2, Mitochondrial (SOD2) (AA 1-222) antibodySOD2 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 8H3F9 unconjugated
anti-Superoxide Dismutase 2, Mitochondrial (SOD2) antibodySOD2 适用: 大鼠 WB, IHC, ELISA, IP, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Superoxide Dismutase 2, Mitochondrial (SOD2) (AA 41-78) antibodySOD2 适用: 人, 小鼠, Pig, 绵羊 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Superoxide Dismutase 2, Mitochondrial (SOD2) (C-Term) antibodySOD2 适用: 人, 大鼠, 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Superoxide Dismutase 2, Mitochondrial (SOD2) (AA 25-222) antibodySOD2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Superoxide Dismutase 2, Mitochondrial (SOD2) (AA 119-130) antibodyVerified SOD2 适用: 人, 大鼠, 小鼠, Pig WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Superoxide Dismutase 2, Mitochondrial (SOD2) antibodySOD2 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Superoxide Dismutase 2, Mitochondrial (SOD2) antibody (Atto 488)SOD2 适用: 大鼠 WB, IHC, ELISA, IP, ICC, IF 宿主: 兔 Polyclonal Atto 488
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- SOD2 (Superoxide Dismutase 2, Mitochondrial (SOD2))
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别名
- SOD2
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背景
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Background: SOD2 (Superoxide Dismutase 2), also called IPO-B or MNSOD, is a mitochondrial matrix enzyme that scavenges oxygen radicals produced by the extensive oxidation-reduction and electron transport reactions occurring in mitochondria. This gene is a member of the iron/manganese superoxide dismutase family. Using a somatic cell hybrid panel containing different segments of chromosome 6, they demonstrated that SOD2 is located in the region 6q25.3-qter which, together with the FISH analysis, indicated that SOD2 is in the distal portion of 6q25. The SOD2 gene encodes an intramitochondrial free radical scavenging enzyme that is the first line of defense against superoxide produced as a byproduct of oxidative phosphorylation. Adeno-associated viral delivery of the human SOD2 gene resulted in suppression of optic nerve degeneration and rescue of retinal ganglion cells. The findings suggested that reactive oxygen species contributed to retinal cell death and optic nerve damage in mice with complex I deficiency, and that expression of SOD2 attenuated the disease process.
Gene Full Name: superoxide dismutase 2
Sequence Similarities: Belongs to the iron/manganese superoxide dismutase family.
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基因ID
- 6648
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UniProt
- P04179
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途径
- Sensory Perception of Sound, Transition Metal Ion Homeostasis, Negative Regulation of intrinsic apoptotic Signaling
抗原
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