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SENP6 抗体 (AA 135-1086) (Fluoro488)

The Fluoro488-conjugated 兔 多克隆 anti-SENP6 antibody (ABIN8043514) specifically detects SENP6 in FACS. The antibody is reactive with 人 samples.
产品编号 ABIN8043514
发货至: 中国
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Quick Overview for SENP6 抗体 (AA 135-1086) (Fluoro488) (ABIN8043514)

抗原

See all SENP6 抗体
SENP6 (SUMO1/sentrin Specific Protease 6 (SENP6))

适用

  • 60
  • 6
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1

宿主

  • 54
  • 5
  • 1

克隆类型

  • 55
  • 5
多克隆

标记

  • 23
  • 7
  • 5
  • 5
  • 5
  • 5
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SENP6 antibody is conjugated to Fluoro488

应用范围

  • 35
  • 29
  • 25
  • 12
  • 11
  • 5
  • 3
Flow Cytometry (FACS)
  • 抗原表位

    • 13
    • 11
    • 7
    • 7
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 135-1086

    原理

    Anti-SENP6 Antibody Fluoro488 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human SENP6 recombinant protein (Position: R135-K1086).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    SENP6 (SUMO1/sentrin Specific Protease 6 (SENP6))

    别名

    SENP6

    背景

    Background: Sentrin-specific protease 6 is an enzyme that in humans is encoded by the SENP6 gene. It is mapped to 6q14.1. Ubiquitin-like molecules (UBLs), such as SUMO1, are structurally related to ubiquitin and can be ligated to target proteins in a similar manner as ubiquitin. However, covalent attachment of UBLs does not result in degradation of the modified proteins. SUMO1 modification is implicated in the targeting of RANGAP1 to the nuclear pore complex, as well as in stabilization of I-kappa-B-alpha from degradation by the 26S proteasome. Like ubiquitin, UBLs are synthesized as precursor proteins, with 1 or more amino acids following the C-terminal glycine-glycine residues of the mature UBL protein. Thus, the tail sequences of the UBL precursors need to be removed by UBL-specific proteases, such as SENP6, prior to their conjugation to target proteins. SENPs also display isopeptidase activity for deconjugation of SUMO-conjugated substrates.

    Gene Full Name: SUMO specific peptidase 6

    基因ID

    26054

    UniProt

    Q9GZR1
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