STIM1 抗体 (AA 42-599) (HRP)
Our Local Distributor
北京 101111
Quick Overview for STIM1 抗体 (AA 42-599) (HRP) (ABIN8043111)
抗原
See all STIM1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 42-599
-
原理
- Anti-STIM1 Antibody HRP Conjugated
-
交叉反应 （详细）
- No cross reactivity with other proteins.
-
预测反应
- Human STIM1 shares 98.2%,98% amino acid (aa) sequence identity with mouse,rat STIM1,respectively.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human STIM1 recombinant protein (Position: E42-L599). Human STIM1 shares 98.2% and 98% amino acid (aa) sequence identity with mouse and rat STIM1, respectively.
-
亚型
- IgG
-
-
anti-Stromal Interaction Molecule 1 (STIM1) (AA 24-685) antibody
STIM1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 5A2 unconjugated
anti-Stromal Interaction Molecule 1 (STIM1) (AA 1-211) antibodySTIM1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Stromal Interaction Molecule 1 (STIM1) (N-Term) antibodySTIM1 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Stromal Interaction Molecule 1 (STIM1) (C-Term) antibodySTIM1 适用: 人, 大鼠, 小鼠 WB, IP, IHC (p), ICC 宿主: 小鼠 Monoclonal CDN3H4 unconjugated
anti-Stromal Interaction Molecule 1 (STIM1) antibodyKD Validated STIM1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB2415 unconjugated Recombinant Antibody
anti-Stromal Interaction Molecule 1 (STIM1) (AA 56-69), (Extracellular), (Lumenal Loop), (N-Term) antibodyKO Validated STIM1 适用: 人 WB, IHC, IP, IF, FACS, IC, LCI 宿主: 兔 Polyclonal unconjugated
anti-Stromal Interaction Molecule 1 (STIM1) (AA 24-686) antibodySTIM1 适用: 人 WB, IHC, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 5A2 unconjugated
anti-Stromal Interaction Molecule 1 (STIM1) (AA 509-538), (C-Term) antibodySTIM1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB19222 unconjugated
anti-Stromal Interaction Molecule 1 (STIM1) (AA 56-69), (Extracellular), (Lumenal Loop), (N-Term) antibody (Atto 550)STIM1 适用: 人 IHC, IF, FACS, IC, LCI 宿主: 兔 Polyclonal Atto 550
anti-Stromal Interaction Molecule 1 (STIM1) (AA 24-686) antibodySTIM1 适用: 人 WB, IF, IHC (p), EIA 宿主: 小鼠 Monoclonal 5A2 unconjugated
-
-
应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
-
有效期
- 12 months
-
-
- STIM1 (Stromal Interaction Molecule 1 (STIM1))
-
别名
- STIM1
-
背景
-
Background: Stromal interaction molecule 1 is a protein that in humans is encoded by the STIM1 gene. STIM1 has a single transmembranedomain, and is localized to the endoplasmic reticulum, and to a lesser extent to the plasma membrane. This gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs). It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region, as well as early hematopoiesis, by mediating attachment to stromal cells. Mutations in this gene are associated with fatal classic Kaposi sarcoma, immunodeficiency due to defects in store-operated calcium entry (SOCE) in fibroblasts, ectodermal dysplasia and tubular aggregate myopathy. This gene is oriented in a head-to-tail configuration with the ribonucleotide reductase 1 gene (RRM1), with the 3' end of this gene situated 1.6 kb from the 5' end of the RRM1 gene. Alternative splicing of this gene results in multiple transcript variants.
Gene Full Name: stromal interaction molecule 1
-
基因ID
- 6786
-
UniProt
- Q13586
-
途径
- TCR Signaling, BCR Signaling
抗原
-
