Stanniocalcin 2 抗体 (AA 51-226) (PE)
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Quick Overview for Stanniocalcin 2 抗体 (AA 51-226) (PE) (ABIN8042526)
抗原
See all Stanniocalcin 2 (STC2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 51-226
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原理
- Anti-Stanniocalcin 2/STC2 Antibody PE Conjugated
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交叉反应 (详细)
- No cross reactivity with other proteins.
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预测反应
- Human STC2 shares 90.3%,89.8% amino acid (aa) sequence identity with mouse,rat STC2,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Stanniocalcin 2/STC2 recombinant protein (Position: A51-Q226). Human STC2 shares 90.3% and 89.8% amino acid (aa) sequence identity with mouse and rat STC2, respectively.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- Stanniocalcin 2 (STC2)
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别名
- STC2
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背景
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Background: Stanniocalcin-2 is a protein that in humans is encoded by the STC2 gene. This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers.
Gene Full Name: stanniocalcin 2
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基因ID
- 8614
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UniProt
- O76061
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途径
- Hormone Activity, ER-Nucleus Signaling, SARS-CoV-2 Protein Interactome
抗原
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