SPON2 抗体 (AA 53-331) (Biotin)
Our Local Distributor
北京 101111
Quick Overview for SPON2 抗体 (AA 53-331) (Biotin) (ABIN8041973)
抗原
See all SPON2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 53-331
-
原理
- Anti-SPON2 Antibody Biotin Conjugated
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human SPON2 recombinant protein (Position: Q53-V331).
-
亚型
- IgG
-
-
anti-Spondin 2 (SPON2) (AA 119-331) antibody
SPON2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Spondin 2 (SPON2) (AA 27-150) antibodySPON2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Spondin 2 (SPON2) (AA 1-331) antibodySPON2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Spondin 2 (SPON2) (Internal Region) antibodyRecent SPON2 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Spondin 2 (SPON2) (Internal Region) antibodyVerified SPON2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Spondin 2 (SPON2) (Internal Region) antibodySPON2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Spondin 2 (SPON2) (AA 190-239) antibodySPON2 适用: 人, 小鼠, 大鼠, 猴, Cow, 豚鼠, 马, 犬, Bat, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Spondin 2 (SPON2) (AA 35-84) antibodySPON2 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 斑马鱼, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Spondin 2 (SPON2) (Internal Region) antibodySPON2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Spondin 2 (SPON2) (Internal Region) antibodySPON2 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
-
有效期
- 12 months
-
-
- SPON2 (Spondin 2 (SPON2))
-
别名
- SPON2
-
背景
-
Background: Spondin 2, also known as mindin, is a protein that in humans is encoded by the SPON2 gene. SPON2 (spondin 2, mindin) is an extracellular matrix protein belonging to the mindin/F-spondin family. The protein has two amino terminal follistatin-like (FS) domains and a carboxy terminal thrombospondin type 1 repeat (TSR) domain. The FS domains mediate interactions between SPON2 and integrins, whereas the TSR domain contributes to the role of SPON2 as a pathogen pattern recognition molecule. In that capacity, SPON2 plays an important role in initiation of the innate immune response. It functions as a pattern recognition molecule within the extracellular matrix, where it binds to microbial pathogens and presents them to immune cells. Interactions between SPON2 and integrins are also critical for inflammatory cell recruitment and T cell priming. In addition to its role in innate immunity, SPON2 has also been shown to play a role in hippocampal neuronal outgrowth, cancer metastasis, and diabetic nephropathy.
Gene Full Name: spondin 2
-
基因ID
- 10417
-
UniProt
- Q9BUD6
抗原
-
