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Splicing Factor 1 抗体 (N-Term) (Biotin)

The 兔 多克隆 anti-Splicing Factor 1 antibody is suitable to detect Splicing Factor 1 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, IHC 和 ELISA.
产品编号 ABIN8041851
发货至: 中国
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Quick Overview for Splicing Factor 1 抗体 (N-Term) (Biotin) (ABIN8041851)

抗原

See all Splicing Factor 1 (SF1) 抗体
Splicing Factor 1 (SF1)

适用

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人, 小鼠, 大鼠

宿主

  • 97
  • 31

克隆类型

  • 93
  • 35
多克隆

标记

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  • 6
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  • 1
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  • 1
  • 1
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  • 1
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This Splicing Factor 1 antibody is conjugated to Biotin

应用范围

  • 80
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  • 7
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  • 2
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 38
    • 29
    • 19
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    原理

    Anti-splicing factor 1/SF1 Antibody Biotin Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    identical to the related rat,mouse sequences.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human splicing factor 1, identical to the related rat and mouse sequences.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    Splicing Factor 1 (SF1)

    别名

    SF1

    背景

    Background: Splicing factor 1 also known as zinc finger protein 162 (ZFM162) is a protein that in humans is encoded by the SF1 gene. This gene encodes a nuclear pre-mRNA splicing factor. The encoded protein specifically recognizes the intron branch point sequence at the 3' splice site, together with the large subunit of U2 auxiliary factor (U2AF), and is required for the early stages of spliceosome assembly. It also plays a role in nuclear pre-mRNA retention and transcriptional repression. The encoded protein contains an N-terminal U2AF ligand motif, a central hnRNP K homology motif and quaking 2 region which bind a key branch-site adenosine within the branch point sequence, a zinc knuckles domain, and a C-terminal proline-rich domain. Alternative splicing results in multiple transcript variants.

    Gene Full Name: splicing factor 1

    Sequence Similarities: Belongs to the BBP/SF1 family.

    基因ID

    7536

    UniProt

    Q15637

    途径

    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Maintenance of Protein Location
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