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Splicing Factor 1 抗体 (AA 160-266) (PE)

The PE-conjugated 小鼠 单克隆 anti-Splicing Factor 1 antibody (Clone 7D9E3) (ABIN8041837) specifically detects Splicing Factor 1 in FACS. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN8041837
发货至: 中国
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Quick Overview for Splicing Factor 1 抗体 (AA 160-266) (PE) (ABIN8041837)

抗原

See all Splicing Factor 1 (SF1) 抗体
Splicing Factor 1 (SF1)

适用

  • 111
  • 97
  • 64
  • 12
  • 10
  • 10
  • 8
  • 8
  • 7
  • 7
  • 5
  • 5
  • 3
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 98
  • 30
小鼠

克隆类型

  • 94
  • 34
单克隆

标记

  • 63
  • 7
  • 6
  • 6
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Splicing Factor 1 antibody is conjugated to PE

应用范围

  • 81
  • 42
  • 41
  • 39
  • 25
  • 18
  • 13
  • 13
  • 13
  • 7
  • 6
  • 2
  • 1
  • 1
Flow Cytometry (FACS)

克隆位点

7D9E3
  • 抗原表位

    • 37
    • 29
    • 20
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 160-266

    原理

    Anti-splicing factor 1 Antibody (monoclonal, 7D9E3) PE Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived human splicing factor 1 recombinant protein (Position: R160-Q266).

    亚型

    IgG2b
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    Splicing Factor 1 (SF1)

    别名

    SF1

    背景

    Background: Splicing factor 1 also known as zinc finger protein 162 (ZFM162) is a protein that in humans is encoded by the SF1 gene. This gene encodes a nuclear pre-mRNA splicing factor. The encoded protein specifically recognizes the intron branch point sequence at the 3' splice site, together with the large subunit of U2 auxiliary factor (U2AF), and is required for the early stages of spliceosome assembly. It also plays a role in nuclear pre-mRNA retention and transcriptional repression. The encoded protein contains an N-terminal U2AF ligand motif, a central hnRNP K homology motif and quaking 2 region which bind a key branch-site adenosine within the branch point sequence, a zinc knuckles domain, and a C-terminal proline-rich domain. Alternative splicing results in multiple transcript variants.

    Gene Full Name: splicing factor 1

    基因ID

    7536

    UniProt

    Q15637

    途径

    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Maintenance of Protein Location
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