SMPD3 抗体 (AA 184-553) (Cy3)
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北京 101111
Quick Overview for SMPD3 抗体 (AA 184-553) (Cy3) (ABIN8041675)
抗原
See all SMPD3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 184-553
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原理
- Anti-SMPD3 Antibody Cy3 Conjugated
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交叉反应 （详细）
- No cross reactivity with other proteins.
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预测反应
- Human SMPD3 shares 88.9% amino acid (aa) sequence identity with both mouse,rat SMPD3.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SMPD3 recombinant protein (Position: F184-D553). Human SMPD3 shares 88.9% amino acid (aa) sequence identity with both mouse and rat SMPD3.
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亚型
- IgG
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anti-Sphingomyelin Phosphodiesterase 3 (SMPD3) (AA 1-655) antibody
SMPD3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Sphingomyelin Phosphodiesterase 3 (SMPD3) (AA 401-655) antibodySMPD3 适用: 人 ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Sphingomyelin Phosphodiesterase 3 (SMPD3) (AA 1-655) antibodySMPD3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Sphingomyelin Phosphodiesterase 3 (SMPD3) (AA 137-165), (N-Term) antibodySMPD3 适用: 人 WB 宿主: 兔 Polyclonal RB39878 unconjugated
anti-Sphingomyelin Phosphodiesterase 3 (SMPD3) antibodySMPD3 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Sphingomyelin Phosphodiesterase 3 (SMPD3) (AA 416-655) antibodySMPD3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Sphingomyelin Phosphodiesterase 3 (SMPD3) (Middle Region) antibodySMPD3 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow Cytometry, 1-3 μg/1x106 cells
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- SMPD3 (Sphingomyelin Phosphodiesterase 3 (SMPD3))
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别名
- SMPD3
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背景
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Background: Sphingomyelin phosphodiesterase 3 is an enzyme that in humans is encoded by the SMPD3 gene. SMPD3 (Sphingomyelin phosphodiesterase 3, also Neutral sphingomyelinase 2/nSMase2) is a 69-74 kDa member of the neutral sphingomyelinase family of enzymes. It is a monomeric Golgi/plasma membrane enzyme that converts sphingomyelin (a plasma membrane lipid) into ceramide and phosphorylcholine. This generates second messenger components that participate in signal transduction. Human SMPD3 is a two transmembrane, 655 amino acids molecule. It contains an N-terminal luminal segment (aa 1-10), a cytoplasmic region (aa 32-64), and one catalytic domain (aa 340-646). Phosphorylation increases its MW to 78 kDa in SDS-PAGE. There is one potential isoform that possesses an Asn substitution for aa 569-587. Over aa 2-655, human SMPD3 shares 91 % aa sequence identity with mouse SMPD3.
Gene Full Name: sphingomyelin phosphodiesterase 3
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基因ID
- 55512
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UniProt
- Q9NY59
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途径
- Hormone Transport
抗原
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