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SPA17 抗体 (AA 1-136) (Fluoro488)

The 兔 多克隆 anti-SPA17 antibody is suitable to detect SPA17 in samples from 人, 大鼠 和 小鼠. It has been validated for FACS.
产品编号 ABIN8041476
发货至: 中国
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Quick Overview for SPA17 抗体 (AA 1-136) (Fluoro488) (ABIN8041476)

抗原

See all SPA17 抗体
SPA17 (Sperm Autoantigenic Protein 17 (SPA17))

适用

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人, 大鼠, 小鼠

宿主

  • 45
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克隆类型

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多克隆

标记

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This SPA17 antibody is conjugated to Fluoro488

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 1-136

    原理

    Anti-SPA17 Antibody Fluoro488 Conjugated

    交叉反应 (详细)

    No cross reactivity with other proteins.

    预测反应

    Human SPA17 shares 75.7% amino acid (aa) sequence identity with mouse SPA17.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human SPA17 recombinant protein (Position: M1-K136). Human SPA17 shares 75.7% amino acid (aa) sequence identity with mouse SPA17.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    SPA17 (Sperm Autoantigenic Protein 17 (SPA17))

    别名

    SPA17

    背景

    Background: Sperm surface protein Sp17 is a protein that in humans is encoded by the SPA17 gene. This gene encodes a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22.

    Gene Full Name: sperm autoantigenic protein 17

    基因ID

    53340

    UniProt

    Q15506
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