SORD 抗体 (AA 8-357) (PE)
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Quick Overview for SORD 抗体 (AA 8-357) (PE) (ABIN8040851)
抗原
See all SORD 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 8-357
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原理
- Anti-Sorbitol Dehydrogenase/SORD Antibody PE Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Sorbitol Dehydrogenase/SORD recombinant protein (Position: N8-P357).
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- SORD (Sorbitol Dehydrogenase (SORD))
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别名
- SORD
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背景
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Background: Sorbitol dehydrogenase is an enzyme that in humans is encoded by the SORD gene. Sorbitol dehydrogenase (SORD) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase, makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications. The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD (+) cofactor.
Gene Full Name: sorbitol dehydrogenase
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基因ID
- 6652
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UniProt
- Q00796
抗原
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