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SLC22A6 抗体 (C-Term) (HRP)

This 兔 多克隆 antibody specifically detects SLC22A6 in WB, IHC 和 ELISA. It exhibits reactivity toward 人 和 大鼠.
产品编号 ABIN8039600
发货至: 中国
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for SLC22A6 抗体 (C-Term) (HRP) (ABIN8039600)

抗原

See all SLC22A6 抗体
SLC22A6 (Solute Carrier Family 22 Member 6 (SLC22A6))

适用

  • 69
  • 32
  • 18
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
人, 大鼠

宿主

  • 69
  • 1

克隆类型

  • 69
  • 1
多克隆

标记

  • 31
  • 6
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This SLC22A6 antibody is conjugated to HRP

应用范围

  • 39
  • 29
  • 25
  • 24
  • 7
  • 4
  • 2
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 19
    • 13
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    原理

    Anti-SLC22A6 Antibody HRP Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    different from the related rat sequence by three amino acids.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human SLC22A6, different from the related rat sequence by three amino acids.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    SLC22A6 (Solute Carrier Family 22 Member 6 (SLC22A6))

    别名

    SLC22A6

    背景

    Background: SLC22A6 (Solute carrier family 22 (organic anion transporter), member 6), also called OAT1 or PAHT, is a protein that in humans is encoded by the SLC22A6 gene, which is also a member of the organic anion transporter (OAT) family of proteins. OAT1 is a transmembrane protein that is expressed in the brain, the placenta, the eyes, smooth muscles, and the basolateral membrane of proximal tubular cells of the kidneys. The SLC22A6 gene is mapped on 11q12.3. It plays a central role in renal organic anion transport. Along with OAT3, OAT1 mediates the uptake of a wide range of relatively small and hydrophilic organic anions from plasma into the cytoplasm of the proximal tubular cells of the kidneys. The SLC22A6 gene contains 10 exons and spans 8.2 kb. OAT1 functions as organic anion exchanger. When the uptake of one molecule of an organic anion is transported into a cell by an OAT1 exchanger, one molecule of an endogenous dicarboxylic acid (such as glutarate, ketoglutarate, etc) is simultaneously transported out of the cell. PAH uptake in Xenopus oocytes injected with OAT1 mRNA was demonstrated by Race et al.

    Gene Full Name: solute carrier family 22 member 6

    Sequence Similarities: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

    基因ID

    9356

    UniProt

    Q4U2R8

    途径

    Dicarboxylic Acid Transport
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