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SMAD7 抗体 (AA 353-388) (PE)

The PE-conjugated 兔 多克隆 anti-SMAD7 antibody (ABIN8038210) specifically detects SMAD7 in FACS. The antibody is reactive with 人 samples.
产品编号 ABIN8038210
发货至: 中国
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Quick Overview for SMAD7 抗体 (AA 353-388) (PE) (ABIN8038210)

抗原

See all SMAD7 抗体
SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))

适用

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宿主

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克隆类型

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多克隆

标记

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This SMAD7 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 353-388

    原理

    Anti-MADH7/SMAD7 Antibody PE Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human MADH7/SMAD7 recombinant protein (Position: R353-Q388).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))

    别名

    SMAD7

    背景

    Background: Mothers against decapentaplegic homolog 7 or SMAD7 is a protein that in humans is encoded by the SMAD7 gene. The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene.

    Gene Full Name: SMAD family member 7

    基因ID

    4092

    UniProt

    O15105

    途径

    Interferon-gamma Pathway, Cell-Cell Junction Organization
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