SMAD7 抗体 (AA 353-388) (Cy3)
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北京 101111
Quick Overview for SMAD7 抗体 (AA 353-388) (Cy3) (ABIN8038203)
抗原
See all SMAD7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 353-388
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原理
- Anti-MADH7/SMAD7 Antibody Cy3 Conjugated
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MADH7/SMAD7 recombinant protein (Position: R353-Q388).
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亚型
- IgG
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anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 1-100) antibody
SMAD7 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 160-260) antibodySMAD7 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1G10 unconjugated
anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 160-260) antibodySMAD7 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3E9 unconjugated
anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 302-400) antibodySMAD7 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3A11 unconjugated
anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 160-260) antibodySMAD7 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4C11 unconjugated
anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 195-224) antibodySMAD7 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB18598 unconjugated
anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 195-224) antibodySMAD7 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 36-247) antibodySMAD7 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 302-400) antibodySMAD7 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3A12 unconjugated
anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 160-260) antibodySMAD7 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Flow Cytometry, 1-3 μg/1x106 cells
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))
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别名
- SMAD7
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背景
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Background: Mothers against decapentaplegic homolog 7 or SMAD7 is a protein that in humans is encoded by the SMAD7 gene. The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene.
Gene Full Name: SMAD family member 7
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基因ID
- 4092
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UniProt
- O15105
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途径
- Interferon-gamma Pathway, Cell-Cell Junction Organization
抗原
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