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SMAD1 抗体 (Middle Region)

The 兔 多克隆 anti-SMAD1 antibody is suitable to detect SMAD1 in samples from 人, 小鼠 和 大鼠. It has been validated for WB.
产品编号 ABIN8038113
发货至: 中国
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Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for SMAD1 抗体 (Middle Region) (ABIN8038113)

抗原

See all SMAD1 抗体
SMAD1 (SMAD, Mothers Against DPP Homolog 1 (SMAD1))

适用

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人, 小鼠, 大鼠

宿主

  • 270
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克隆类型

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多克隆

标记

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This SMAD1 antibody is un-conjugated

应用范围

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Western Blotting (WB)

质量等级

Carrier-free
  • 抗原表位

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    Middle Region

    原理

    Anti-SMAD1 Antibody

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    different from the related mouse sequence by two amino acids,and from the related rat sequence by five amino acids.

    产品特性

    Anti-SMAD1 Antibody. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human SMAD1, different from the related mouse sequence by two amino acids, and from the related rat sequence by five amino acids.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    SMAD1 (SMAD, Mothers Against DPP Homolog 1 (SMAD1))

    别名

    SMAD1

    背景

    Background: SMADs are proteins that modulate the activity of transforming growth factor beta ligands. The SMADs, often in complex with other SMADs/CoSMAD, act as transcription factors that regulate the expression of certain genes. It was concluded that targeted ubiquitination of SMADs may serve to control both embryonic development and a wide variety of cellular responses to TGF-beta signals. R-Smads or receptor regulated Smads are a class of proteins that include SMAD1, SMAD2, SMAD3, SMAD5, and SMAD8. In response to signals by the TGF-β superfamily of ligands these proteins associate with receptor kinases and are phosphorylated at an SSXS motif at their extreme C-terminus. These proteins then typically bind to the common mediator Smad or co-SMAD SMAD4.

    Gene Full Name: SMAD family member 1

    Sequence Similarities: Belongs to the dwarfin/SMAD family.

    分子量

    52 kDa

    基因ID

    4086

    UniProt

    Q15797

    途径

    Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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