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SMAD1 抗体 (Middle Region) (PE)

The PE-conjugated 兔 多克隆 anti-SMAD1 antibody (ABIN8038111) specifically detects SMAD1 in FACS. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN8038111
发货至: 中国
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Room 801-803
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Quick Overview for SMAD1 抗体 (Middle Region) (PE) (ABIN8038111)

抗原

See all SMAD1 抗体
SMAD1 (SMAD, Mothers Against DPP Homolog 1 (SMAD1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This SMAD1 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    Middle Region

    原理

    Anti-SMAD1 Antibody PE Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    different from the related mouse sequence by two amino acids,and from the related rat sequence by five amino acids.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human SMAD1, different from the related mouse sequence by two amino acids, and from the related rat sequence by five amino acids.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    SMAD1 (SMAD, Mothers Against DPP Homolog 1 (SMAD1))

    别名

    SMAD1

    背景

    Background: SMADs are proteins that modulate the activity of transforming growth factor beta ligands. The SMADs, often in complex with other SMADs/CoSMAD, act as transcription factors that regulate the expression of certain genes. It was concluded that targeted ubiquitination of SMADs may serve to control both embryonic development and a wide variety of cellular responses to TGF-beta signals. R-Smads or receptor regulated Smads are a class of proteins that include SMAD1, SMAD2, SMAD3, SMAD5, and SMAD8. In response to signals by the TGF-β superfamily of ligands these proteins associate with receptor kinases and are phosphorylated at an SSXS motif at their extreme C-terminus. These proteins then typically bind to the common mediator Smad or co-SMAD SMAD4.

    Gene Full Name: SMAD family member 1

    Sequence Similarities: Belongs to the dwarfin/SMAD family.

    基因ID

    4086

    UniProt

    Q15797

    途径

    Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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