SIVA1 抗体 (AA 1-141) (Biotin)
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北京 101111
Quick Overview for SIVA1 抗体 (AA 1-141) (Biotin) (ABIN8037860)
抗原
See all SIVA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-141
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原理
- Anti-SIVA/SIVA1 Antibody Biotin Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SIVA/SIVA1 recombinant protein (Position: M1-T141).
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亚型
- IgG
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- SIVA1 (SIVA1, Apoptosis-Inducing Factor (SIVA1))
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别名
- SIVA1
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背景
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Background: Apoptosis regulatory protein Siva is a protein that in humans is encoded by the SIVA1 gene. This gene encodes an E3 ubiquitin ligase that regulates cell cycle progression, cell proliferation and apoptosis. The N-terminus of this protein binds to the cytoplasmic tail of the CD27 antigen, a member of the tumor necrosis factor receptor (TNFR) superfamily. In response to UV radiation-induced DNA damage, this protein has been shown to mediate the ubiquitination of proliferating cell nuclear antigen (PCNA), an important step in translesion DNA synthesis.
Gene Full Name: SIVA1 apoptosis inducing factor
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基因ID
- 10572
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UniProt
- O15304
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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