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SIRT2 抗体 (Middle Region) (Fluoro647)

The Fluoro647-conjugated 兔 多克隆 anti-SIRT2 antibody (ABIN8037781) specifically detects SIRT2 in FACS. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN8037781
发货至: 中国
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Quick Overview for SIRT2 抗体 (Middle Region) (Fluoro647) (ABIN8037781)

抗原

See all SIRT2 抗体
SIRT2 (Sirtuin 2 (SIRT2))

适用

  • 98
  • 77
  • 63
  • 8
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 92
  • 14
  • 1

克隆类型

  • 73
  • 34
多克隆

标记

  • 53
  • 10
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SIRT2 antibody is conjugated to Fluoro647

应用范围

  • 69
  • 22
  • 22
  • 21
  • 21
  • 18
  • 15
  • 15
  • 11
  • 3
  • 2
  • 2
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 11
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    原理

    Anti-SIRT2 Antibody Fluoro647 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    different from the related mouse,rat sequences by three amino acids.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human SIRT2, different from the related mouse and rat sequences by three amino acids.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    SIRT2 (Sirtuin 2 (SIRT2))

    别名

    SIRT2

    背景

    Background: SIRT2 is a predominantly cytoplasmic protein that colocalizes with microtubules. This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. SIRT2 is mapped to 19q13.2. It is able to cause radioactivity to be transferred from (32P) NAD to bovine serum albumin (BSA). According to researches, SIRT2 can act as a bona fide tubulin deacetylase. SIRT2 was found to deacetylate lys40 of alpha-tubulin both in vitro and in vivo. SIRT2 is also a regulator of mitotic progression that acts downstream from CDC14B in a pathway regulating mitotic exit or subsequent cytokinesis. What's more, SIRT2 is an important regulator of programmed necrosis.

    Gene Full Name: sirtuin 2

    Sequence Similarities: Belongs to the sirtuin family. Class I subfamily.

    基因ID

    22933

    UniProt

    Q8IXJ6
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