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SIM2 抗体 (AA 337-609) (HRP)

This 兔 多克隆 antibody specifically detects SIM2 in ELISA, WB 和 IHC. It exhibits reactivity toward 人, 小鼠, 大鼠 和 猴.
产品编号 ABIN8037734
发货至: 中国
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Quick Overview for SIM2 抗体 (AA 337-609) (HRP) (ABIN8037734)

抗原

See all SIM2 抗体
SIM2 (Single-Minded Homolog 2 (SIM2))

适用

  • 43
  • 18
  • 16
  • 13
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠, 猴

宿主

  • 40
  • 3
  • 1

克隆类型

  • 42
  • 2
多克隆

标记

  • 17
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SIM2 antibody is conjugated to HRP

应用范围

  • 17
  • 16
  • 13
  • 13
  • 11
  • 6
  • 4
  • 3
  • 1
  • 1
ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 15
    • 12
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 337-609

    原理

    Anti-SIM2 Antibody HRP Conjugated

    交叉反应 (详细)

    No cross reactivity with other proteins.

    预测反应

    Human SIM2 shares 85.8% amino acid (aa) sequence identity with mouse SIM2.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human SIM2 recombinant protein (Position: Y337-R609). Human SIM2 shares 85.8% amino acid (aa) sequence identity with mouse SIM2.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    SIM2 (Single-Minded Homolog 2 (SIM2))

    别名

    SIM2

    背景

    Background: Single-minded homolog 2 is a protein that in humans is encoded by the SIM2 gene. This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants.

    Gene Full Name: SIM bHLH transcription factor 2

    基因ID

    6493

    UniProt

    Q14190
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