SIM2 抗体 (AA 337-609) (Fluoro488)
Our Local Distributor
北京 101111
Quick Overview for SIM2 抗体 (AA 337-609) (Fluoro488) (ABIN8037730)
抗原
See all SIM2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 337-609
-
原理
- Anti-SIM2 Antibody Fluoro488 Conjugated
-
交叉反应 (详细)
- No cross reactivity with other proteins.
-
预测反应
- Human SIM2 shares 85.8% amino acid (aa) sequence identity with mouse SIM2.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human SIM2 recombinant protein (Position: Y337-R609). Human SIM2 shares 85.8% amino acid (aa) sequence identity with mouse SIM2.
-
亚型
- IgG
-
-
-
-
应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
-
有效期
- 12 months
-
-
- SIM2 (Single-Minded Homolog 2 (SIM2))
-
别名
- SIM2
-
背景
-
Background: Single-minded homolog 2 is a protein that in humans is encoded by the SIM2 gene. This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants.
Gene Full Name: SIM bHLH transcription factor 2
-
基因ID
- 6493
-
UniProt
- Q14190
抗原
-