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SIRPA 抗体 (C-Term) (APC)

The APC-conjugated 兔 多克隆 anti-SIRPA antibody (ABIN8037625) specifically detects SIRPA in FACS. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN8037625
发货至: 中国
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Quick Overview for SIRPA 抗体 (C-Term) (APC) (ABIN8037625)

抗原

See all SIRPA 抗体
SIRPA (Signal-Regulatory Protein alpha (SIRPA))

适用

  • 143
  • 72
  • 60
  • 10
  • 9
  • 3
  • 3
  • 3
人, 小鼠, 大鼠

宿主

  • 109
  • 57
  • 8
  • 7

克隆类型

  • 108
  • 72
  • 1
多克隆

标记

  • 80
  • 16
  • 11
  • 9
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SIRPA antibody is conjugated to APC

应用范围

  • 93
  • 89
  • 38
  • 37
  • 30
  • 29
  • 14
  • 12
  • 10
  • 9
  • 3
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 24
    • 16
    • 12
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    原理

    Anti-SIRP Alpha/SIRPA Antibody APC Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human SIRP Alpha/SIRPA.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    SIRPA (Signal-Regulatory Protein alpha (SIRPA))

    别名

    SIRPA

    背景

    Background: The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. This gene and its product share very high similarity with several other members of the SIRP family. These related genes are located in close proximity to each other on chromosome 20p13. Multiple alternatively spliced transcript variants have been determined for this gene.

    Gene Full Name: signal regulatory protein alpha

    基因ID

    140885

    UniProt

    P78324
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