SESN1 抗体 (AA 1-275) (HRP)
Our Local Distributor
北京 101111
Quick Overview for SESN1 抗体 (AA 1-275) (HRP) (ABIN8036651)
抗原
See all SESN1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-275
-
原理
- Anti-SESN1 Antibody HRP Conjugated
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human SESN1 recombinant protein (Position: M1-A275).
-
亚型
- IgG
-
-
anti-Sestrin 1 (SESN1) (AA 1-551) antibody
SESN1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Sestrin 1 (SESN1) (AA 312-341), (C-Term) antibodySESN1 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB18601 unconjugated
anti-Sestrin 1 (SESN1) antibodySESN1 适用: 人 WB, FACS, ICC 宿主: 兔 Monoclonal 24GB1040 unconjugated Recombinant Antibody
anti-Sestrin 1 (SESN1) antibodySESN1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Sestrin 1 (SESN1) (AA 1-551) antibodySESN1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Sestrin 1 (SESN1) (AA 271-370) antibodySESN1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Sestrin 1 (SESN1) (AA 14-43), (N-Term) antibodySESN1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB18600 unconjugated
anti-Sestrin 1 (SESN1) (AA 224-337) antibodySESN1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sestrin 1 (SESN1) (AA 45-492) antibodySESN1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sestrin 1 (SESN1) (AA 375-424) antibodySESN1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, Bat, 小鸡, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
-
有效期
- 12 months
-
-
- SESN1 (Sestrin 1 (SESN1))
-
别名
- SESN1
-
背景
-
Background: Sestrin 1, also known as p53-regulated protein PA26, is a protein that in humans is encoded by the SESN1 gene. This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene Full Name: sestrin 1
-
基因ID
- 27244
-
UniProt
- Q9Y6P5
抗原
-
