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SESN1 抗体 (AA 1-275) (Fluoro594)

The 兔 多克隆 anti-SESN1 antibody is suitable to detect SESN1 in samples from 人, 小鼠 和 大鼠. It has been validated for FACS.
产品编号 ABIN8036649
发货至: 中国
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Quick Overview for SESN1 抗体 (AA 1-275) (Fluoro594) (ABIN8036649)

抗原

See all SESN1 抗体
SESN1 (Sestrin 1 (SESN1))

适用

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人, 小鼠, 大鼠

宿主

  • 71
  • 3

克隆类型

  • 62
  • 12
多克隆

标记

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This SESN1 antibody is conjugated to Fluoro594

应用范围

  • 57
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Flow Cytometry (FACS)
  • 抗原表位

    • 16
    • 12
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    • 1
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    AA 1-275

    原理

    Anti-SESN1 Antibody Fluoro594 Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human SESN1 recombinant protein (Position: M1-A275).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    SESN1 (Sestrin 1 (SESN1))

    别名

    SESN1

    背景

    Background: Sestrin 1, also known as p53-regulated protein PA26, is a protein that in humans is encoded by the SESN1 gene. This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

    Gene Full Name: sestrin 1

    基因ID

    27244

    UniProt

    Q9Y6P5
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