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SERPINH1 抗体 (AA 247-418) (Biotin)

The Biotin-conjugated 兔 多克隆 anti-SERPINH1 antibody (ABIN8036281) specifically detects SERPINH1 in WB, ELISA 和 IHC. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN8036281
发货至: 中国
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Quick Overview for SERPINH1 抗体 (AA 247-418) (Biotin) (ABIN8036281)

抗原

See all SERPINH1 抗体
SERPINH1 (Serpin Family H Member 1 (SERPINH1))

适用

  • 86
  • 47
  • 45
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 69
  • 28

克隆类型

  • 60
  • 37
多克隆

标记

  • 44
  • 7
  • 7
  • 5
  • 5
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SERPINH1 antibody is conjugated to Biotin

应用范围

  • 70
  • 36
  • 32
  • 21
  • 17
  • 15
  • 9
  • 3
  • 2
  • 2
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 11
    • 8
    • 7
    • 6
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 247-418

    原理

    Anti-Hsp47/SERPINH1 Antibody Biotin Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human Hsp47 shares 97% amino acid (aa) sequence identity with both mouse,rat Hsp47.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Hsp47 recombinant protein (Position: D247-L418). Human Hsp47 shares 97% amino acid (aa) sequence identity with both mouse and rat Hsp47.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    SERPINH1 (Serpin Family H Member 1 (SERPINH1))

    别名

    SERPINH1

    背景

    Background: Heat shock protein 47, also known as SERPINH1 or HSP47, is a serpin which serves as a human chaperone protein for collagen. This protein is a member of the serpin superfamily of serine proteinase inhibitors. Its expression is induced by heat shock. The protein localizes to the endoplasmic reticulum lumen and binds collagen, thus it is thought to be a molecular chaperone involved in the maturation of collagen molecules. Autoantibodies to this protein have been found in patients with rheumatoid arthritis. It has been found that HSP47 monitors the integrity of the triple helix of type I procollagen at the ER/cis-Golgi boundary and, when absent, the rate of transit from the ER to the Golgi is increased and the helical structure is compromised.

    Gene Full Name: serpin family H member 1

    Sequence Similarities: Belongs to the serpin family.

    基因ID

    871

    UniProt

    P50454
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