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SPTLC1 抗体 (C-Term) (Biotin)

The Biotin-conjugated 兔 多克隆 anti-SPTLC1 antibody (ABIN8035891) specifically detects SPTLC1 in WB, IHC 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN8035891
发货至: 中国
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Quick Overview for SPTLC1 抗体 (C-Term) (Biotin) (ABIN8035891)

抗原

See all SPTLC1 抗体
SPTLC1 (serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))

适用

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宿主

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克隆类型

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多克隆

标记

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This SPTLC1 antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
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    C-Term

    原理

    Anti-SPTLC1 Antibody Biotin Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    different from the related mouse sequence by three amino acids.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human SPTLC1, different from the related mouse sequence by three amino acids.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    SPTLC1 (serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))

    别名

    SPTLC1

    背景

    Background: SPTLC1 (Serine palmitoyltransferase, long chain base subunit 1), also known as SPT1, LCB1, is a protein which in humans is encoded by the SPTLC1 gene. Dawkins et al. (2001) noted that the SPTLC1 gene maps to chromosome 9q22.1-q22.3. Serine palmitoyltransferase, which consists of two different subunits, is the initial enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl CoA to 3-oxosphinganine with pyridoxal 5'-phosphate as a cofactor. The product of this gene is the long chain base subunit 1 of serine palmitoyltransferase. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified.

    Gene Full Name: serine palmitoyltransferase long chain base subunit 1

    基因ID

    10558

    UniProt

    O15269
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