SEZ6L 抗体 (AA 662-953) (Biotin)
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北京 101111
Quick Overview for SEZ6L 抗体 (AA 662-953) (Biotin) (ABIN8035274)
抗原
See all SEZ6L 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 662-953
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原理
- Anti-SEZ6L Antibody Biotin Conjugated
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SEZ6L recombinant protein (Position: E662-E953).
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亚型
- IgG
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anti-Seizure Related 6 Homolog Like (SEZ6L) (AA 701-800) antibody
SEZ6L 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Seizure Related 6 Homolog Like (SEZ6L) (AA 662-953) antibodySEZ6L 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- SEZ6L (Seizure Related 6 Homolog Like (SEZ6L))
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别名
- SEZ6L
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背景
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Background: Seizure 6-like protein is a protein that in humans is encoded by the SEZ6L gene. SEZ6L (Seizure 6-Like protein, also BSRP-B in rodent) is a 200 kDa member of the SEZ6 family of proteins. It is expressed in the plasma membrane and ER of CNS neurons and lung bronchiolar epithelium, and likely regulates PKC alpha activation. Mature human SEZ6L is a 996 amino acid (aa) type I transmembrane protein. It contains a 930 aa extracellular domain (ECD) (aa 29-958) plus a 45 aa cytoplasmic tail. The ECD shows three CUB domains and five short consensus repeats (SCRs). There are multiple isoforms possible for SEZ6L. One shows a deletion of aa 933-943, and a second shows the same deletion coupled to a Thr substitution for aa 803-867. A third isoform contains a Leu substitution for aa 867-943. An alternative start site is reported at Met228. This start site may occur individually, or be accompanied by a deletion of aa 932-944, the same deletion of aa 932-944 coupled to a Thr substitution for aa 803-867, or a duel deletion of aa 869-945 and 1016-1024. Over aa 29-958, human BSRP-B is 80 % aa identical to mouse BSRP-B.
Gene Full Name: seizure related 6 homolog like
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基因ID
- 23544
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UniProt
- Q9BYH1
抗原
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