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RUNX1 抗体 (Middle Region) (APC)

This 兔 多克隆 antibody specifically detects RUNX1 in FACS. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN8034092
发货至: 中国
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Quick Overview for RUNX1 抗体 (Middle Region) (APC) (ABIN8034092)

抗原

See all RUNX1 抗体
RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))

适用

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人, 小鼠, 大鼠

宿主

  • 150
  • 17
  • 1
  • 1

克隆类型

  • 150
  • 20
多克隆

标记

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This RUNX1 antibody is conjugated to APC

应用范围

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  • 15
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  • 6
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  • 1
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Flow Cytometry (FACS)
  • 抗原表位

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    • 9
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    Middle Region

    原理

    Anti-RUNX1/AML1 Antibody APC Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    identical to the related mouse,rat sequences.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human RUNX1, identical to the related mouse and rat sequences.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))

    别名

    RUNX1

    背景

    Background: Runt-related transcription factor 1 (RUNX1), also known as AML1 or CBFA2, is a protein that in humans is encoded by the RUNX1 gene. It belongs to the Runt-related transcription factor (RUNX) family of genes which are also called core binding factor-α (CBFα). RUNX1 is mapped to 21q22.12. RUNX1 is a transcription factor that regulates the differentiation of hematopoietic stem cells into mature blood cells. RUNX proteins form a heterodimeric complex with CBFβ which confers increased DNA binding and stability to the complex. Chromosomal translocations involving the RUNX1 gene are associated with several types of leukemia including M2 AML. Mutations in RUNX1 are implicated in cases of breast cancer.

    Gene Full Name: RUNX family transcription factor 1

    Sequence Similarities: Contains 1 Runt domain.

    基因ID

    861

    UniProt

    Q01196
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