RING1 抗体 (AA 6-387)
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北京 101111
Quick Overview for RING1 抗体 (AA 6-387) (ABIN8033162)
抗原
See all RING1 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 6-387
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原理
- Anti-RING1 Antibody
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交叉反应 (详细)
- No cross reactivity with other proteins.
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预测反应
- Human RING1 shares 96.3%,96.6% amino acid (aa) sequence identity with mouse,rat RING1,respectively.
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产品特性
- Anti-RING1 Antibody. Tested in WB, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human RING1 recombinant protein (Position: N6-K387). Human RING1 shares 96.3% and 96.6% amino acid (aa) sequence identity with mouse and rat RING1, respectively.
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亚型
- IgG
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应用备注
- Western blot, 0.5-1 μg/mL, Human, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- RING1 (Ring Finger Protein 1 (RING1))
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别名
- RING1
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背景
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Background: E3 ubiquitin-protein ligase RING1 is an enzyme that in humans is encoded by the RING1 gene. This gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain. The gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL and HKE4.
Gene Full Name: ring finger protein 1
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分子量
- 50 kDa
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基因ID
- 6015
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UniProt
- Q06587
抗原
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