RING1 抗体 (AA 6-387) (Biotin)
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Quick Overview for RING1 抗体 (AA 6-387) (Biotin) (ABIN8033152)
抗原
See all RING1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 6-387
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原理
- Anti-RING1 Antibody Biotin Conjugated
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交叉反应 (详细)
- No cross reactivity with other proteins.
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预测反应
- Human RING1 shares 96.3%,96.6% amino acid (aa) sequence identity with mouse,rat RING1,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human RING1 recombinant protein (Position: N6-K387). Human RING1 shares 96.3% and 96.6% amino acid (aa) sequence identity with mouse and rat RING1, respectively.
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亚型
- IgG
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- RING1 (Ring Finger Protein 1 (RING1))
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别名
- RING1
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背景
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Background: E3 ubiquitin-protein ligase RING1 is an enzyme that in humans is encoded by the RING1 gene. This gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain. The gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL and HKE4.
Gene Full Name: ring finger protein 1
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基因ID
- 6015
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UniProt
- Q06587
抗原
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