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RPS6 抗体 (N-Term) (Fluoro647)

The Fluoro647-conjugated 小鼠 单克隆 anti-RPS6 antibody (Clone 2H7) (ABIN8032930) specifically detects RPS6 in FACS. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN8032930
发货至: 中国
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Quick Overview for RPS6 抗体 (N-Term) (Fluoro647) (ABIN8032930)

抗原

See all RPS6 抗体
RPS6 (Ribosomal Protein S6 (RPS6))

适用

  • 165
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  • 12
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  • 1
人, 小鼠, 大鼠

宿主

  • 172
  • 22
  • 2
小鼠

克隆类型

  • 153
  • 43
单克隆

标记

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This RPS6 antibody is conjugated to Fluoro647

应用范围

  • 157
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  • 11
  • 3
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Flow Cytometry (FACS)

克隆位点

2H7
  • 抗原表位

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    • 1
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    • 1
    • 1
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    N-Term

    原理

    Anti-RPS6 Antibody (monoclonal, 2H7) Fluoro647 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    identical to the related mouse,rat sequences.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human RPS6, identical to the related mouse and rat sequences.

    亚型

    IgG1
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    RPS6 (Ribosomal Protein S6 (RPS6))

    别名

    RPS6

    背景

    Background: Ribosomal protein S6  (rpS6) is a component of the 40S ribosomal subunit and is therefore thought to be involved in regulating translation. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. While the true function of rpS6 is currently under investigation, studies have shown that it is involved in the regulation of cell size, cell proliferation, and glucose homeostasis.

    Gene Full Name: ribosomal protein S6

    基因ID

    6194

    UniProt

    P62753

    途径

    Carbohydrate Homeostasis, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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