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RTKN2 抗体 (AA 1-572) (Fluoro647)

The 兔 多克隆 anti-RTKN2 antibody is suitable to detect RTKN2 in samples from 人, 小鼠 和 大鼠. It has been validated for FACS.
产品编号 ABIN8032302
发货至: 中国
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Quick Overview for RTKN2 抗体 (AA 1-572) (Fluoro647) (ABIN8032302)

抗原

See all RTKN2 抗体
RTKN2 (Rhotekin 2 (RTKN2))

适用

  • 45
  • 23
  • 14
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 41
  • 4

克隆类型

  • 43
  • 2
多克隆

标记

  • 18
  • 5
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This RTKN2 antibody is conjugated to Fluoro647

应用范围

  • 26
  • 24
  • 23
  • 7
  • 2
  • 2
Flow Cytometry (FACS)
  • 抗原表位

    • 12
    • 12
    • 8
    • 7
    • 1
    • 1
    AA 1-572

    原理

    Anti-RTKN2 Antibody Fluoro647 Conjugated

    预测反应

    Human RTKN2 shares 71.8% amino acid (aa) sequence identity with mouse RTKN2.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human RTKN2 recombinant protein (Position: M1-D572). Human RTKN2 shares 71.8% amino acid (aa) sequence identity with mouse RTKN2.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    RTKN2 (Rhotekin 2 (RTKN2))

    别名

    RTKN2

    背景

    Background: Rhotekin 2 is a protein in humans that is encoded by the RTKN2 gene. The RTKN2 gene encodes a protein known as Rhotekin-2, which is involved in various cellular processes, including cytoskeletal organization, cell migration, and signal transduction. RTKN2 interacts with Rho GTPases, particularly RhoA, and modulates their activity to regulate actin cytoskeleton dynamics and cell morphology. This protein plays a role in cell adhesion and migration, with implications for tissue development, wound healing, and cancer metastasis. Additionally, RTKN2 has been linked to synaptic plasticity and neuronal development in the brain. Dysregulation of RTKN2 expression or function has been associated with neurological disorders, cardiovascular diseases, and cancer progression. Elucidating the molecular mechanisms underlying RTKN2's diverse functions is crucial for understanding its physiological roles and its potential as a therapeutic target for various diseases.

    Gene Full Name: rhotekin 2

    基因ID

    219790

    UniProt

    Q8IZC4
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