RTKN2 抗体 (AA 1-572) (APC)
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Quick Overview for RTKN2 抗体 (AA 1-572) (APC) (ABIN8032300)
抗原
See all RTKN2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-572
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原理
- Anti-RTKN2 Antibody APC Conjugated
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预测反应
- Human RTKN2 shares 71.8% amino acid (aa) sequence identity with mouse RTKN2.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human RTKN2 recombinant protein (Position: M1-D572). Human RTKN2 shares 71.8% amino acid (aa) sequence identity with mouse RTKN2.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- RTKN2 (Rhotekin 2 (RTKN2))
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别名
- RTKN2
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背景
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Background: Rhotekin 2 is a protein in humans that is encoded by the RTKN2 gene. The RTKN2 gene encodes a protein known as Rhotekin-2, which is involved in various cellular processes, including cytoskeletal organization, cell migration, and signal transduction. RTKN2 interacts with Rho GTPases, particularly RhoA, and modulates their activity to regulate actin cytoskeleton dynamics and cell morphology. This protein plays a role in cell adhesion and migration, with implications for tissue development, wound healing, and cancer metastasis. Additionally, RTKN2 has been linked to synaptic plasticity and neuronal development in the brain. Dysregulation of RTKN2 expression or function has been associated with neurological disorders, cardiovascular diseases, and cancer progression. Elucidating the molecular mechanisms underlying RTKN2's diverse functions is crucial for understanding its physiological roles and its potential as a therapeutic target for various diseases.
Gene Full Name: rhotekin 2
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基因ID
- 219790
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UniProt
- Q8IZC4
抗原
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