LATS1,2 (AA 641-740) 抗体 (Biotin)
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北京 101111
Quick Overview for LATS1,2 (AA 641-740) 抗体 (Biotin) (ABIN753555)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 641-740
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特异性
- This antibody will detects both LATS1 and LATS2.
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Dog,Cow,Horse,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human LATS2
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亚型
- IgG
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anti-LATS1,2 (AA 641-740) antibody
适用: 人, 小鼠, 大鼠 ELISA, WB, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-LATS1,2 (Ser116) antibody适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- LATS1,2
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别名
- LATS1/2
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背景
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Synonyms: Serine/threonine-protein kinase LATS1, LATS1, Large tumor suppressor homolog 1, WARTS protein kinase, h-warts, WARTS, Serine/threonine-protein kinase LATS2, LATS2, Kinase phosphorylated during mitosis protein, Large tumor suppressor homolog 2, Serine/threonine-protein kinase kpm, Warts-like kinase, KPM
Background: This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression. [provided by RefSeq].
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基因ID
- 26524, 9113
抗原
-
