Rhotekin 抗体 (AA 255-554)
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北京 101111
Quick Overview for Rhotekin 抗体 (AA 255-554) (ABIN8032292)
抗原
See all Rhotekin (RTKN) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 255-554
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原理
- Anti-RTKN Antibody
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-RTKN Antibody. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human RTKN recombinant protein (Position: R255-Q554).
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亚型
- IgG
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- Rhotekin (RTKN)
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别名
- RTKN
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背景
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Background: Rhotekin is a protein that in humans is encoded by the RTKN gene. This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene Full Name: rhotekin
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分子量
- 70 kDa
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基因ID
- 6242
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UniProt
- Q9BST9
抗原
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