Rhotekin 抗体 (AA 255-554) (Fluoro594)
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北京 101111
Quick Overview for Rhotekin 抗体 (AA 255-554) (Fluoro594) (ABIN8032286)
抗原
See all Rhotekin (RTKN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 255-554
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原理
- Anti-RTKN Antibody Fluoro594 Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human RTKN recombinant protein (Position: R255-Q554).
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- Rhotekin (RTKN)
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别名
- RTKN
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背景
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Background: Rhotekin is a protein that in humans is encoded by the RTKN gene. This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene Full Name: rhotekin
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基因ID
- 6242
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UniProt
- Q9BST9
抗原
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