GRAF 抗体 (AA 584-791) (FITC)
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Quick Overview for GRAF 抗体 (AA 584-791) (FITC) (ABIN8032122)
抗原
See all GRAF (ARHGAP26) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 584-791
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原理
- Anti-GRAF/ARHGAP26 Antibody FITC Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human GRAF/ARHGAP26 recombinant protein (Position: S584-E791).
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- GRAF (ARHGAP26) (rho GTPase Activating Protein 26 (ARHGAP26))
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别名
- ARHGAP26
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背景
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Background: Rho GTPase activating protein 26 (ARHGAP26) also known as GTPase Regulator Associated with Focal Adhesion Kinase (GRAF) is a protein that in humans is encoded by the ARHGAP26 gene. Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Multiple transcript variants encoding different isoforms have been found for this gene.
Gene Full Name: Rho GTPase activating protein 26
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基因ID
- 23092
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UniProt
- Q9UNA1
抗原
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