RGMB 抗体 (AA 47-404) (HRP)
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北京 101111
Quick Overview for RGMB 抗体 (AA 47-404) (HRP) (ABIN8032079)
抗原
See all RGMB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 47-404
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原理
- Anti-DRAGON/RGMB Antibody HRP Conjugated
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human DRAGON/RGMB recombinant protein (Position: D47-R404).
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亚型
- IgG
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anti-RGM Domain Family, Member B (RGMB) antibody
RGMB 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB56812 unconjugated
anti-RGM Domain Family, Member B (RGMB) (Center) antibodyRGMB 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-RGM Domain Family, Member B (RGMB) (AA 380-407), (C-Term) antibodyRGMB 适用: 人 WB 宿主: 兔 Polyclonal RB37543 unconjugated
anti-RGM Domain Family, Member B (RGMB) (AA 376-406), (C-Term) antibodyRGMB 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- RGMB (RGM Domain Family, Member B (RGMB))
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别名
- RGMB
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背景
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Background: Repulsive guidance molecule B (RGMb), also known as DRAGON (DRG11-responsive axonal guidance and outgrowth of neurite), is a bone morphogenetic protein (BMP) co-receptor of the repulsive guidance molecule family. In humans this protein is encoded by the RGMB gene. RGMB is a glycosylphosphatidylinositol (GPI)-anchored member of the repulsive guidance molecule family (see also RGMA and RGMC) and contributes to the patterning of the developing nervous system. There is a potential association between RGMs and cancer bone metastasis, as RGMs coordinate bone morphogenetic protein (BMP) signaling. RGMB may act as a negative regulator in vitro in breast cancer and prostate cancer through BMP signalling. Furthermore, aberrant expression of RGMs was indicated in breast cancer. The perturbed expression was associated with disease progression and poor prognosis.
Gene Full Name: repulsive guidance molecule BMP co-receptor b
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基因ID
- 285704
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UniProt
- Q6NW40
抗原
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