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Replication Termination Factor 2 (RTF2) (AA 4-306) 抗体 (Fluoro550)

The 兔 多克隆 anti-Replication Termination Factor 2 antibody is suitable to detect Replication Termination Factor 2 in samples from 人. It has been validated for FACS.
产品编号 ABIN8031600
发货至: 中国
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Quick Overview for Replication Termination Factor 2 (RTF2) (AA 4-306) 抗体 (Fluoro550) (ABIN8031600)

抗原

Replication Termination Factor 2 (RTF2)

适用

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人

宿主

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兔

克隆类型

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多克隆

标记

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Fluoro550

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

    AA 4-306

    原理

    Anti-RTF2 Antibody Fluoro550 Conjugated

    预测反应

    Human RTF2 shares 87.8%,88.1% amino acid (aa) sequence identity with mouse,rat RTF2,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human RTF2 recombinant protein (Position: D4-F306). Human RTF2 shares 87.8% and 88.1% amino acid (aa) sequence identity with mouse and rat RTF2, respectively.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    Replication Termination Factor 2 (RTF2)

    别名

    RTF2

    背景

    Background: Replication termination factor 2 is a protein that in humans is encoded by the RTF2 gene. Replication Termination Factor 2, often abbreviated as RTF2, is a protein involved in the regulation and termination of DNA replication processes in eukaryotic cells. It plays a crucial role in ensuring the accurate completion of DNA synthesis during cell division by coordinating the termination of replication forks at specific sites along the DNA strands. RTF2 functions by interacting with other proteins and DNA sequences to facilitate the orderly disassembly of the replication machinery and the prevention of unnecessary re-replication of genomic regions. Its activity is tightly regulated to maintain genomic stability and fidelity, making it a key player in cell cycle control mechanisms. Studies on RTF2 have provided insights into the molecular mechanisms governing DNA replication termination and its implications for cellular function and genome maintenance.

    Gene Full Name: replication termination factor 2

    基因ID

    51507

    UniProt

    Q9BY42
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