RFXANK 抗体 (AA 29-260)
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北京 101111
Quick Overview for RFXANK 抗体 (AA 29-260) (ABIN8031287)
抗原
See all RFXANK 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 29-260
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原理
- Anti-RFXANK Antibody
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交叉反应 (详细)
- No cross reactivity with other proteins.
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预测反应
- Human RFXANK shares 85.1% amino acid (aa) sequence identity with mouse RFXANK.
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产品特性
- Anti-RFXANK Antibody. Tested in WB, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human RFXANK recombinant protein (Position: E29-E260). Human RFXANK shares 85.1% amino acid (aa) sequence identity with mouse RFXANK.
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亚型
- IgG
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- RFXANK (Regulatory Factor X-Associated Ankyrin Containing Protein (RFXANK))
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别名
- RFXANK
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背景
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Background: DNA-binding protein RFXANK is a protein that in humans is encoded by the RFXANK gene. Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. This protein contains ankyrin repeats involved in protein-protein interactions. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group B. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Gene Full Name: regulatory factor X associated ankyrin containing protein
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分子量
- 34 kDa
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基因ID
- 8625
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UniProt
- O14593
抗原
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