RIPK2 抗体 (C-Term) (Biotin)
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Quick Overview for RIPK2 抗体 (C-Term) (Biotin) (ABIN8030958)
抗原
See all RIPK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-RIP2/RIPK2 Antibody Biotin Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- different from the related rat,mouse sequences by one amino acid.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human RIP2, different from the related rat and mouse sequences by one amino acid.
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亚型
- IgG
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anti-Receptor-Interacting Serine-threonine Kinase 2 (RIPK2) (AA 431-540) antibody
RIPK2 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 6F7 unconjugated
anti-Receptor-Interacting Serine-threonine Kinase 2 (RIPK2) (AA 458-488), (C-Term) antibodyRIPK2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB03318 unconjugated
anti-Receptor-Interacting Serine-threonine Kinase 2 (RIPK2) (AA 431-540) antibodyRIPK2 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 7F5 unconjugated
anti-Receptor-Interacting Serine-threonine Kinase 2 (RIPK2) (AA 1-294) antibodyRIPK2 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Receptor-Interacting Serine-threonine Kinase 2 (RIPK2) (AA 1-540) antibodyRIPK2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Receptor-Interacting Serine-threonine Kinase 2 (RIPK2) (AA 458-488) antibodyRIPK2 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Receptor-Interacting Serine-threonine Kinase 2 (RIPK2) (AA 432-540) antibodyRIPK2 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Receptor-Interacting Serine-threonine Kinase 2 (RIPK2) (pSer176) antibodyRIPK2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Receptor-Interacting Serine-threonine Kinase 2 (RIPK2) (N-Term) antibodyRIPK2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Receptor-Interacting Serine-threonine Kinase 2 (RIPK2) (AA 39-68), (N-Term) antibodyRIPK2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB33776 unconjugated
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- RIPK2 (Receptor-Interacting Serine-threonine Kinase 2 (RIPK2))
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别名
- RIPK2
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背景
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Background: RIPK2 (Receptor-interacting serine/threonine-protein kinase 2), also known as CARD3, CARDIAK, RICK, RIP2, is an enzyme that in humans is encoded by the RIPK2 gene. It has 540-amino acid protein in length. Northern blot analysis revealed that RICK is expressed in various human tissues as 2.5- and 1.8-kb mRNAs that differ due to alternative polyadenylation. RICK is a novel kinase that may regulate apoptosis induced by the FAS receptor pathway. This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappa B and inducer of apoptosis in response to various stimuli, CARDIAK (CARD-containing ICE-associated kinase) specifically interacted with the CARD of ICE/caspase-1, and this interaction correlated with the processing of pro-caspase-1 and the formation of the active caspase-1 p20 subunit.
Gene Full Name: receptor interacting serine/threonine kinase 2
Sequence Similarities: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
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基因ID
- 8767
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UniProt
- O43353
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途径
- TCR Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades
抗原
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