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CBL 抗体 (pTyr700)

Name: CBL 抗体 (pTyr700)
SKU: ABIN753418
Availability: OutOfStock

CBL 适用: 人, 大鼠 ELISA, IHC (p), IF (p), IF (cc), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

Paraformaldehyde-fixed, paraffin embedded human lung carcinoma tissue, Antigen retrieval by boiling in sodium citrate buffer(pH6) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes, Blocking buffer (normal goat serum) at 37°C for 20min, Antibody incubation with Rabbit Anti-CBL2 (Tyr700) Polyclonal Antibody, Unconjugated at 1:500 overnight at 4°C, followed by a conjugated secondary and DAB staining (CBL 抗体 (pTyr700))

IHC (p)

1 image

产品编号 ABIN753418

发货至: 中国

Datasheet as PDF

抗原 See all CBL 抗体

CBL (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL))
抗原表位
28

22

19

17

8

7

7

5

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pTyr700
适用
157

74

63

2

2

1

1
人, 大鼠
宿主
139

16

3

1
兔
Compatible Secondaries
克隆类型
141

18
多克隆
标记
70

9

8

8

8

8

8

8

6

6

4

4

4

4

4
This CBL antibody is un-conjugated
应用范围
79

51

51

46

32

25

20

11

9

9

5

3

1

1

1
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

交叉反应

人, 大鼠

预测反应

Mouse,Dog,Cow,Pig,Horse

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic phosphopeptide derived from human C CBL around the phosphorylation site of Tyr700

亚型

IgG

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CBL 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 6D12 unconjugated

anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) (AA 1-906) antibody
CBL 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated

anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) (AA 1-906) antibody
CBL 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) (Internal Region) antibody
CBL 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) (AA 548-847) antibody
CBL 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) (pTyr770) antibody
CBL 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) antibody
CBL 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) (pTyr674) antibody
CBL 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) (AA 637-906) antibody
CBL 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
抗原

CBL (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL))

别名

CBL2 (CBL 产品)

别名

4732447J05Rik antibody, Cbl-2 antibody, c-Cbl antibody, cbl antibody, C-CBL antibody, CBL2 antibody, FRA11B antibody, NSLL antibody, RNF55 antibody, c-cbl-like antibody, RGD1561386 antibody, Casitas B-lineage lymphoma antibody, Cbl proto-oncogene antibody, Cbl antibody, CBL antibody

背景

Synonyms: C CBL Tyr700, CBL2 Tyr700, CBL2 Y700, p-CBL2 Tyr700, p-CBL2 Y700, C CBL, Cas-Br-M murine ecotropic retroviral transforming sequence, Casitas B lineage lymphoma proto oncogene, CBL 2,E3 ubiquitin protein ligase CBL, Oncogene CBL2, Proto oncogene c CBL, RGD1561386, RING finger protein 55, RNF55v Signal transduction protein CBL, 4732447J05Rik, CBL_HUMAN.
Background: This gene is a proto-oncogene that encodes a RING finger E3 ubiquitin ligase. The encoded protein is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates. This protein also contains an N-terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine-phosphorylated substrates and target them for proteasome degradation. As such it functions as a negative regulator of many signal transduction pathways. This gene has been found to be mutated or translocated in many cancers including acute myeloid leukaemia. Mutations in this gene are also the cause of Noonan syndrome-like disorder. [provided by RefSeq, Mar 2012]

基因ID

867

途径

TCR Signaling, Interferon-gamma Pathway, EGFR Signaling Pathway, EGFR Downregulation, VEGFR1 Specific Signals