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REST 抗体 (AA 110-1097) (FITC)

The FITC-conjugated 兔 多克隆 anti-REST antibody (ABIN8030842) specifically detects REST in FACS. The antibody is reactive with 人 samples.
产品编号 ABIN8030842
发货至: 中国
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Quick Overview for REST 抗体 (AA 110-1097) (FITC) (ABIN8030842)

抗原

See all REST 抗体
REST (RE1-Silencing Transcription Factor (REST))

适用

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宿主

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克隆类型

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多克隆

标记

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This REST antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 110-1097

    原理

    Anti-REST Antibody FITC Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human REST shares 62.9%,59.6% amino acid (aa) sequence identity with mouse,rat REST,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human REST recombinant protein (Position: E110-E1097). Human REST shares 62.9% and 59.6% amino acid (aa) sequence identity with mouse and rat REST, respectively.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    REST (RE1-Silencing Transcription Factor (REST))

    别名

    REST

    背景

    Background: This gene was initially identified as a transcriptional repressor that represses neuronal genes in non-neuronal tissues. However, depending on the cellular context, this gene can act as either an oncogene or a tumor suppressor. The encoded protein is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regulator of neurogenesis. Alternatively spliced transcript variants have been described.

    Gene Full Name: RE1 silencing transcription factor

    基因ID

    5978

    UniProt

    Q13127

    途径

    Negative Regulation of Hormone Secretion, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Chromatin Binding, Positive Regulation of Endopeptidase Activity
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