RASA1 抗体 (C-Term)
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Quick Overview for RASA1 抗体 (C-Term) (ABIN8030726)
抗原
See all RASA1 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- C-Term
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原理
- Anti-RASA1 Antibody
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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预测反应
- different from the related rat sequence by one amino acid.
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产品特性
- Anti-RASA1 Antibody. Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human RASA1, different from the related rat sequence by one amino acid.
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亚型
- IgG
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anti-RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) (AA 948-1047) antibody
RASA1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2C12 unconjugated
anti-RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) (AA 948-1047) antibodyRASA1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1E6 unconjugated
anti-RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) antibodyRASA1 适用: 人, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) (AA 403-596) antibodyRASA1 适用: 人 WB, ELISA, IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) (AA 1-870) antibodyRASA1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) (C-Term) antibodyRASA1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) (AA 201-500) antibodyRASA1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) (C-Term) antibodyRASA1 适用: 人 WB, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) (AA 1-870) antibodyRASA1 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
anti-RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) (AA 625-675) antibodyRASA1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, 0.1-0.5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- RASA1 (RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1))
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别名
- RASA1
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背景
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Background: RASA1, also known as RAS p21 protein activator 1, is a 120- kDacytosolic human protein. The protein encoded by this gene is located in the cytoplasm and is part of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. Mutations leading to changes in the binding sites of either protein are associated with basal cell carcinomas. Mutations also have been associated with hereditary capillary malformations (CM) with or without arteriovenous malformations (AVM) and Parkes Weber syndrome. Alternative splicing results in two isoforms where the shorter isoform, lacking the N-terminal hydrophobic region but retaining the same activity, appears to be abundantly expressed in placental but not adult tissues.
Gene Full Name: RAS p21 protein activator 1
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分子量
- 100 kDa
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基因ID
- 5921
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UniProt
- P20936
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途径
- Regulation of Actin Filament Polymerization, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals
抗原
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