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RORC 抗体 (AA 286-511) (Biotin)

This 兔 多克隆 antibody specifically detects RORC in WB, ELISA 和 IHC. It exhibits reactivity toward 人.
产品编号 ABIN8030549
发货至: 中国
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Quick Overview for RORC 抗体 (AA 286-511) (Biotin) (ABIN8030549)

抗原

See all RORC 抗体
RORC (RAR-Related Orphan Receptor C (RORC))

适用

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宿主

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克隆类型

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多克隆

标记

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This RORC antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    AA 286-511

    原理

    Anti-ROR gamma/RORC Antibody Biotin Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human ROR gamma/RORC recombinant protein (Position: Q286-E511).

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    RORC (RAR-Related Orphan Receptor C (RORC))

    别名

    RORC

    背景

    Background: RAR-related orphan receptor gamma (RORγ) is a protein that in humans is encoded by the RORC (RAR-related orphan receptor C) gene. The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene.

    Gene Full Name: RAR related orphan receptor C

    基因ID

    6097

    UniProt

    P51449

    途径

    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
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